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Parmesan cheese, salami, cornichons, smoked fish…what do they all have in common?

Besides being excellent additions to a cheese andcharcuterie board, these delicious foods are high in tyramine.

What is tyramine?

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registered dietitian nutritionist and founder ofKid Food Explorers

Tyramine, a natural substance in our bodies, helps manage blood pressure and brain signals, Lebovitz explains.

Deriving from the amino acidtyrosine, its also found in common foods and drinks.

(Its in the same chemical group as theneurotransmitters dopamine, norepinephrine, and serotonin.)

An image of four wine glasses on a wooden surface

But MAOIsalsoprevent the breakdown of excess tyramine in the bodybecause remember, tyramine is related to those neurotransmitters.

Those taking MAOIs may avoidcertain foods1, and same goes for people prone to migraines.

Its all about how your body processes tyramine, she explains.

Young woman mixing ice coffee

Cutting back on foods high in it can make a big difference in managing these conditions.

What foods contain tyramine?

Thats because microbesconvert tyrosine (the amino acid) into tyramine as the foods age2.

Cropped shot of young woman shopping in the dairy section of a supermarket. She is reading the nutrition label on a container of fresh organic healthy natural yoghurt

registered dietitian nutritionist and founder ofKid Food Explorers

So the more aged or fermented something is, the more likely it is to have lots of tyramine.

Therefore, individuals sensitive to tyramine may also benefit from moderating their caffeine intake, she says.

For fresh produce, consume it within a couple of days of purchase.

Two cups with coffee and green tea on a beige background.

For canned or frozen foods, use them soon after opening, too, she advises.

When it comes to fresh animal proteins, she suggests eating or freezing them the same day of purchase.

Should everyone limit tyramine?

red pigment in a wooden spoon

No, not everyone needs to stress about tyramine.

Others may be more sensitive to it than others, and some people may process it just fine.

Meeting with a dietitian [who can] offer personalized guidance may also be helpful.

Van den Eynde, Vincent et al.

The Prescribers Guide to the MAOI Diet-Thinking Through Tyramine Troubles.Psychopharmacology bulletinvol.

52,2 (2022): 73-116.

Anderegg, Janine et al.

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